Autoimmune Disease

Conditions where the immune system mistakenly attacks the body’s own tissues, causing pain and inflammation.
Autoimmune Disease Overview
Autoimmune diseases occur when the immune system mistakenly targets healthy tissue instead of foreign invaders, causing inflammation and damage in affected organs or joints. More than 80 autoimmune conditions have been identified, including rheumatoid arthritis, lupus, and Sjögren’s disease, each affecting different parts of the body. Symptoms often flare and then improve over time, and many of these conditions cause chronic pain that can be managed alongside disease-specific treatment.
Learn more about autoimmune diseases from MedlinePlus, the health information service of the U.S. National Library of Medicine.
Common Symptoms
Common Causes
Related Treatments at Republic
When to Seek Care
See a specialist if you have persistent joint pain, unexplained fatigue, or recurring inflammation, especially alongside a diagnosed or suspected autoimmune condition.


